29 Nov 2021

Participation of the ABG group in the III Spanish Conference on Biocatalysis

 The Applied Biocatalysis Group has been present in the III Spanish Conference on Biocatalysis (JEB 2021) that was held in Murcia between Thursday 25 and Saturday 27 November 2021. This congress was organized by the Spanish Biotechnology Society (SEBIOT) and the University of Murcia, giving continuity to the editions held in Madrid in 2015, and in Oviedo in 2018. Fadia Cervantes presented her work on glucose isomerase immobilization, José Luis González-Alfonso on phloretin glycosylation and Marina Minguet on the discovery of novel chitinolytic enzymes. We also contributed to other works in collaboration with several GLICOENZ members.

8 Nov 2021

Article published in the José Luis Garcı́a Fierro Festschrift special issue of I&EC Research


The journal Industrial & Engineering Chemistry Research is publishing a collection of papers honoring Professor José Luis García Fierro of Institute of Catalysis and Petrochemistry, CSIC (Spain) to recognize his contributions to applied chemistry, mainly in catalysis.

We have had the honour to participate in this issue with a work that describes a fast, simple, and easily scalable process for polyglucosylation of the flavonoid rutin. This can be used as a strategy to enhance its aqueous solubility and bioavailability. We isolated and chemically characterized six glucosides. The addition of amyloglucosidase STA1 allowed us to increase the monoglucoside yield up to 2-fold. Glucosylated derivatives of rutin also possess a great potential to improve the dissolution and absorption of poorly water-soluble pharmaceuticals.

“Polyglucosylation of rutin catalyzed by cyclodextrin glucanotransferase from Geobacillus sp.: Optimization and chemical characterization of products”. J.L. González-Alfonso, A. Poveda, M. Arribas, Y. Hirose, M. Fernández-Lobato, A.O. Ballesteros, J. Jiménez-Barbero & F.J. Plou. Industrial and Engineering Chemistry Research (2021). https://doi.org/10.1021/acs.iecr.1c03070